Small Molecule Drug Discovery Primer 201
*This microcourse includes optional CPE Credits and is powered by Biotech Primer, a trusted leader in life science training that simplifies complex topics for non-scientists.
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Optional CPE Credits: 1.5
Overview:
Small Molecule Drug Discovery Primer 201 builds upon the foundational knowledge from Small Molecule Drug Discovery Primer 101. This class takes a deep dive into early screening techniques, including discovery platforms, high-throughput screening, and novel target identification. It breaks down the strategies used for lead optimization, along with drug design methodology and approaches. Uncover the crucial criteria for transitioning from discovery to development, including how to rigorously evaluate data from in silico, in vitro, and in vivo assets.
- Section 1: Overview: Explains the steps involved in drug discovery and how drug discovery fits into the entire process of bringing a new therapeutic to market.
- Section 2: Early Screening: Describes common drug discovery platforms, explains target identification processes and screening considerations, and discusses the need for high throughput screening of molecules in drug discovery.
- Section 3: Target Validation: Defines target validation processes and target selection and discusses some common questions that need to be answered about target-drug interactions.
- Session 4: Lead Optimization: Criteria Explains lead optimization activities, discusses drug design methods, defines ADMET, and gives an example of a screening pathway.
- Session 5: Discovery to Development: Transition Criteria Lists the typical criteria for advancement of potential drug development candidates.
By the end of the course, participants will be able to:
- Acquire an in-depth understanding of the rigorous drug discovery process for small molecules.
- Explore the impact and results of typical drug development discovery platforms.
- Master the art of performing lead optimization activities and learn the strategies that lead to remarkable outcomes.
- Make well-informed decisions by justifying and selecting the most effective testing methods at each critical stage of the drug discovery process.
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