Lantern Pharma Reports Promising Phase 1a Results for LP‑184, Showing Durable Control in Tough Cancers

Lantern Pharma Reports Promising Phase 1a Results for LP‑184, Showing Durable Control in Tough Cancers

Lantern Pharma’s investigational drug LP‑184 showed durable disease control in a Phase 1a trial of 63 heavily pre‑treated advanced cancer patients, meeting all safety and tolerability endpoints. The study established a recommended Phase 2 dose of 0.39 mg/kg, with a disease‑control rate of ~54% at or above therapeutic doses. Patients with DNA‑damage‑repair mutations, including NSCLC and thymic carcinoma, remain on treatment for 12–23+ months, showing meaningful tumor reductions. These results support Lantern’s precision‑oncology strategy and plans for multiple biomarker‑guided Phase 1b/2 trials across several tumor types.  

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