The Colossal Wolly Mouse - A Scientific Breakthrough

The Colossal Wolly Mouse - A Scientific Breakthrough

Colossal Biosciences has achieved a groundbreaking milestone in multiplexed genome engineering with the birth of the Colossal Woolly Mouse—mice genetically engineered to exhibit multiple key mammoth-like traits for adaptation to cold climates. By successfully modifying seven genes at once, Colossal's team has produced mice with significantly altered coat color, texture, and thickness, closely resembling the woolly mammoth’s defining characteristics. This breakthrough validates the ability to express ancient traits using insights from computational analysis of 59 woolly, Columbian, and steppe mammoth genomes spanning from 3,500 to over 1.2 million years ago, confirming these genetic pathways as essential targets for mammoth de-extinction.

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